Peer-Reviewed Journal Details
Mandatory Fields
Authors
Brint EK, MacSharry J, Fanning A, Shanahan F, Quigley EM
Year
2011
Month
February
Journal
The American Journal of Gastroenterology
Title
Differential expression of toll-like receptors in patients with irritable bowel syndrome.
Status
Validated
Times Cited
()
Optional Fields
Keywords
Volume
106
Issue
2
Start Page
329
End Page
336
Abstract
The pathogenesis of irritable bowel syndrome (IBS) is poorly understood. One contributory factor may be low-grade mucosal inflammation, perhaps initiated by the microbiota. Toll-like receptors (TLRs) are a family of pathogen-recognition receptors of the innate immune system. The aim of this study was to evaluate the potential involvement of TLRs in IBS to further understand the involvement of the innate immune system in this complex disorder.
Publisher Location
ISBN / ISSN
Edition
URL
DOI Link
10.1038/ajg.2010.438
Grant Details
Funding Body
Grant Details